CH3COCOOH, formerly known as tartaric acid (De Brenztr-aubensure), alias 2-oxopropionic acid, acetoformic acid, looking to light yellow liquid, smell of acetic acid It is one of the intermediate products involved in the basic metabolism of the entire organism. Due to α-keto acid and strong reactivity, molecular formula: C3H4O3, molecular weight: 88.06, CAS number: 127-17-3.
It is related to many enzyme reactions. Among the common respiration sources of animals and plants, carbohydrates are the most commonly used, and the reaction pathway is from the formation of hexose diphosphate through pyrose phosphate to pyruvate. There are various forms of anaerobic decomposition, such as lactic acid produced by muscles, yeast fermentation to produce carbon dioxide and ethanol under anaerobic conditions, and all the reaction pathways to pyruvate are the same, but the final reaction is somewhat different. And it decomposes under aerobic state, and pyruvate can be completely oxidized through the tricarboxylic acid cycle. It can be considered as an effective way to obtain energy.
In this sense, pyruvate is located at the junction of anaerobic decomposition and aerobic decomposition, and is an extremely important intermediate product. As shown in the structure of α-keto acid, the reaction is extremely easy to proceed. In most cases, even if the concentration is increased, it will not accumulate in the tissues and cause harmful effects. In addition, pyruvic acid can directly produce alanine because it can be combined with the transamination reaction, so it also plays an important role in nitrogen metabolism. In addition, it reacts with CoA to form acetyl CoA, which also has an important relationship with fatty acid metabolism.
Qualitative analysis can use phenylhydrazine, α- or β-naphthol or 10,4-dinitrophenylhydrazine, and quantitative analysis can use lactate dehydrogenase. Its metabolic product is mainly phenylpyruvate, which is excreted with urine.
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