Medical plastic bottle packaging sealing performance test method

In order to prevent the influence of light, heat, oxygen, etc. on the drugs, and ensure that the drugs are free from moisture and deterioration during the effective period, medicinal plastic bottles should have good sealing properties. The relevant national standards have made clear provisions on this, and this is also an important indicator for various production companies.

Medical plastic bottles are widely used because of their advantages of light weight, high strength, no breakage, good sealing performance, moisture resistance, and hygiene, meeting the special requirements of pharmaceutical packaging, and being able to be directly used for pharmaceutical packaging without washing and drying. Oral solid drugs and oral liquid medicine packaging. In order to prevent the influence of light, heat, oxygen, etc. on the drugs, and ensure that the drugs are free from moisture and deterioration during the effective period, medicinal plastic bottles should have good sealing properties. The relevant national standards have made clear provisions on this, and this is also an important indicator for various production companies. Next Labthink Languang combined with MFY-01 sealing tester will briefly introduce the sealing performance test of medicinal plastic bottles.

Sealing performance refers to the reliability of medical plastic bottle sealing, which can ensure the integrity of the entire product packaging seal. In order to ensure that the medicines are free of moisture and deterioration during the validity period, medicinal plastic bottles should have good sealing properties. The relevant national standards have made clear regulations for this: Take a certain number of medicinal plastic bottles, each bottle is loaded Amount of glass balls, tighten the cap (torque shown in the table below).

Then put it into a container with a suction device, immersed in water, vacuum to a vacuum of 27kpa, maintain for 2 minutes, the bottle can not have water or bubble phenomenon. Labthink's MFY-01 Sealing Tester utilizes the principle of vacuum to vacuum the vacuum chamber to generate differential pressure between the inside and outside of the sample immersed in water, and to observe gas escape conditions in the sample to determine the sealing performance of the sample. Or through the vacuum chamber vacuum, make the sample produce internal and external pressure difference, observe the expansion of the sample and release the vacuum after the recovery of the shape of the sample to determine the sealing performance of the sample. The experiment process only needs to input the corresponding pressure value and time, the instrument can realize automatic test, convenient operation, friendly human-computer interaction. The above method is based on the principle of visual inspection. It is a qualitative test method. If you want to quantitatively test the sealing and leakage performance of the package, you can use the positive pressure method to seal the performance test equipment, such as Labthink's LSSD-01 leak and Sealing strength tester.

Of course, after ensuring that the medical plastic bottle's sealing index is qualified, it is necessary to control other indicators such as oxygen barrier and moisture resistance to ensure the quality of the product during the shelf life. Jinan Languang Electromechanical Technology Co., Ltd. would like to take this opportunity to increase exchanges and cooperation with enterprises and institutions in the industry.